- Run through 26 replayable levels in 3 distinct episodes from the movie that take place in a laboratory-like house in the town of Black Falls, a factory, and a castle with a moat
- Play as Nose Noseworthy, Loogie Short, Toe Thompson and Helvetica Black, each with their own special jump and unique ability
- Activate special jumps and unique abilities like the alien and wasp hover jumps, telekinesis super-attack, invincibility, and growth and shrink ray guns for sticky situations
- Use the stylus to draw temporary platforms to jump on and get around obstacles or create a shield to avoid dangerous threats
- Face a multitude of enemies like booger monsters, bomb shooting crocodiles, poison spitting snakes, bats, and sparking robots
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